5 Long-Term Side Effects of Paracetamol: Paracetamol, or acetaminophen, is one of the most commonly used non-prescription drugs to relieve pain as well as reduce fever. It can treat symptoms ranging from headaches to body aches. It is however not so known for its long-term or high-dose associated health risks that many people tend to ignore; besides, its use isn’t that bad in the case of spontaneous as well as inferior use.
Because paracetamol is processed in the liver, chronic or excessive use would result in toxicity therein. On a long-term basis, this may cause liver inflammation or scarring (cirrhosis) or even to liver failure, especially when it is taken with alcohol or other drugs.
Long-term paracetamol use, especially in high doses, may exhibit a declining function of the kidneys. Over the years, chronic kidney disease could develop, or worse, the kidney could fail, especially among the elderly and those with underlying diseases.
Evidence points to the assertion that using paracetamol over a long time could predispose one to hypertension (high blood pressure); this is particularly true for persons who use it daily or make liberal dosing.
Recurrent use in pregnancy has been faintly associated with problems experienced during development by babies-in particular, delayed speech, unwanted behaviors, or asthmatic symptoms. Not much evidence is yet available on this subject, and why long-term exposure should be avoided unless prescribed.
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Paracetamol can bring about severe allergic skin reactions but is rare in presenting with such side effects in long-term use. Such as Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN), both potentially life-threatening states involving peeling skin, blisters, and fever.
Use Wisely Stay Safe
Paracetamol still remains an effective medicine, provided there is proper use. The main thing, though, is moderation with advice from health practitioners, particularly when one is mostly relying on it. Follow dosage recommendations and see a doctor for the long-term management of pain.
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